Representative binding poses of Compound 1: ZINC000169302042, Compound 2: ZINC000169724085, Compound 3: ZINC000253389129, Compound 4: ZINC000255260827, Compound 5: ZINC000299817569, derived from molecular docking studies into hMC4R. Hydrogen bonds are depicted with dashed yellow lines, pi-pi stacking with dashed blue lines, and Ca2+-coordination with black lines.

 
 
  Part of: Giakoumopoulou S, Christodoulou P, Matsoukas M-T, Panagiotopoulos V, Cavouras D, Kritsi E (2025) Leveraging machine learning and molecular docking techniques to predict novel melanocortin-4 receptor agonists. Folia Medica 67(3): e150583. https://doi.org/10.3897/folmed.67.e150583