<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//TaxonX//DTD Taxonomic Treatment Publishing DTD v0 20100105//EN" "https://foliamedica.bg/nlm/tax-treatment-NS0.dtd">
<article xmlns:tp="http://www.plazi.org/taxpub" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="research-article" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">87</journal-id>
      <journal-id journal-id-type="index">urn:lsid:arphahub.com:pub:A116C711-4C18-5A38-8F1E-5E97753A8A64</journal-id>
      <journal-title-group>
        <journal-title xml:lang="en">Folia Medica</journal-title>
        <abbrev-journal-title xml:lang="en">FM</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">0204-8043</issn>
      <issn pub-type="epub">1314-2143</issn>
      <publisher>
        <publisher-name>Plovdiv Medical University</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.3897/folmed.68.e156282</article-id>
      <article-id pub-id-type="publisher-id">156282</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Case Report</subject>
        </subj-group>
        <subj-group subj-group-type="scientific_subject">
          <subject>Cardiovascular surgery</subject>
          <subject>Thoracic surgery</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Surgical management of postintubation tracheal stenosis: a clinical case</article-title>
      </title-group>
      <contrib-group content-type="authors">
        <contrib contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Yavorov</surname>
            <given-names>Boyko</given-names>
          </name>
          <email xlink:type="simple">yavoroff@hotmail.com</email>
          <uri content-type="orcid">https://orcid.org/0009-0003-3980-3599</uri>
          <xref ref-type="aff" rid="A1">1</xref>
          <xref ref-type="aff" rid="A2">2</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Aleksiev</surname>
            <given-names>Vladimir</given-names>
          </name>
          <uri content-type="orcid">https://orcid.org/0009-0004-7860-6632</uri>
          <xref ref-type="aff" rid="A1">1</xref>
          <xref ref-type="aff" rid="A2">2</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Stoev</surname>
            <given-names>Hristo</given-names>
          </name>
          <xref ref-type="aff" rid="A3">3</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Karlyukov</surname>
            <given-names>Martin</given-names>
          </name>
          <xref ref-type="aff" rid="A2">2</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Shterev</surname>
            <given-names>Filip</given-names>
          </name>
          <xref ref-type="aff" rid="A4">4</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Kartev</surname>
            <given-names>Stanislav</given-names>
          </name>
          <xref ref-type="aff" rid="A4">4</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Vazhev</surname>
            <given-names>Zaprin</given-names>
          </name>
          <xref ref-type="aff" rid="A1">1</xref>
          <xref ref-type="aff" rid="A2">2</xref>
        </contrib>
      </contrib-group>
      <aff id="A1">
        <label>1</label>
        <addr-line content-type="verbatim">Department of Cardiovascular Surgery, Medical University of Plovdiv, Plovdiv, Bulgaria</addr-line>
        <institution>Kaspela University Hospital, Thoracic surgery clinic</institution>
        <addr-line content-type="city">Plovdiv</addr-line>
        <country>Bulgaria</country>
      </aff>
      <aff id="A2">
        <label>2</label>
        <addr-line content-type="verbatim">Thoracic Surgery Clinic, Kaspela University Hospital, Plovdiv, Bulgaria</addr-line>
        <institution>Medical University of Plovdiv, Department of Cardiovascular surgery</institution>
        <addr-line content-type="city">Plovdiv</addr-line>
        <country>Bulgaria</country>
      </aff>
      <aff id="A3">
        <label>3</label>
        <addr-line content-type="verbatim">Heart and Brain Hospital, Pleven, Bulgaria</addr-line>
        <institution>Heart and Brain Hospital</institution>
        <addr-line content-type="city">Pleven</addr-line>
        <country>Bulgaria</country>
      </aff>
      <aff id="A4">
        <label>4</label>
        <addr-line content-type="verbatim">First Department of Internal Diseases, Section of Pulmonology and Phthisiatry, Medical University of Plovdiv, Plovdiv, Bulgaria</addr-line>
        <institution>Medical University of Plovdiv, First Department of Internal Diseases, Section of Pulmonology and Phthisiatry</institution>
        <addr-line content-type="city">Plovdiv</addr-line>
        <country>Bulgaria</country>
      </aff>
      <author-notes>
        <fn fn-type="corresp">
          <p><bold>Corresponding author</bold>: Boyko Yavorov, Department of Cardiovascular Surgery, Medical University of Plovdiv, 15A Vassil Aprilov, 4002 Plovdiv, Bulgaria; Email: <email xlink:type="simple">yavoroff@hotmail.com</email></p>
        </fn>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2026</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>31</day>
        <month>08</month>
        <year>2026</year>
      </pub-date>
      <volume>68</volume>
      <issue>4</issue>
      <elocation-id>e156282</elocation-id>
      <uri content-type="arpha" xlink:href="http://openbiodiv.net/4B0DBCE8-AB4E-5F18-A0B5-4C097AE57597">4B0DBCE8-AB4E-5F18-A0B5-4C097AE57597</uri>
      <history>
        <date date-type="received">
          <day>18</day>
          <month>04</month>
          <year>2025</year>
        </date>
        <date date-type="accepted">
          <day>20</day>
          <month>06</month>
          <year>2025</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Boyko Yavorov, Vladimir Aleksiev, Hristo Stoev, Martin Karlyukov, Filip Shterev, Stanislav Kartev, Zaprin Vazhev</copyright-statement>
        <license license-type="creative-commons-attribution" xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <abstract>
        <p>
          <bold>Abstract</bold>
        </p>
        <p>Postintubation tracheal stenosis, a complication of prolonged mechanical ventilation via orotracheal intubation, often presents with stridor and dyspnea due to tracheal fibrosis and scarring, typically distal to the cricoid cartilage. Its complex nature necessitates a multidisciplinary approach and expertise in tracheal, thyroid, mediastinal, and neurovascular surgical techniques. This case report details the clinical management of postintubation tracheal stenosis, highlighting a successful tracheal resection and anastomosis procedure.</p>
        <p>A patient, S.A., presented at the Thoracic Surgery Department, UMHAT Kaspela, Plovdiv, with respiratory distress, including stridor and dyspnea, following 10 days of mechanical ventilation for aspiration pneumonia. The diagnostic workup included thoracic computed tomography (<abbrev xlink:title="computed tomography">CT</abbrev>), video bronchoscopy, echocardiography, and pulmonary function tests. Surgical intervention involved Kocher’s cervicotomy, tracheal mobilization, circular resection of the stenotic segment, and termino-terminal anastomosis. Intraoperative video bronchoscopy confirmed stenosis location and post-anastomosis tracheal integrity. The patient recovered uneventfully and was discharged in satisfactory condition.</p>
        <p>Surgical management of postintubation tracheal stenosis, when guided by early diagnosis, precise imaging, and a multidisciplinary approach, yields favorable outcomes. This case underscores the importance of surgical expertise and meticulous planning in achieving successful results.</p>
      </abstract>
      <kwd-group>
        <label>Keywords</label>
        <kwd>cervicotomy</kwd>
        <kwd>tracheal stenosis</kwd>
        <kwd>tracheal resection</kwd>
        <kwd>postintubation stenosis</kwd>
      </kwd-group>
    </article-meta>
    <notes>
      <sec sec-type="Citation" id="sec1">
        <title>Citation</title>
        <p>Yavorov B, Aleksiev V, Stoev H, Karlyukov M, Shterev F, Kartev S, Vazhev Z. Surgical management of postintubation tracheal stenosis: a clinical case. Folia Med (Plovdiv) 2026;68(4):е156282. <ext-link ext-link-type="doi" xlink:href="10.3897/folmed.68.e156282">doi: 10.3897/folmed.68.e156282</ext-link>.</p>
      </sec>
    </notes>
  </front>
  <body>
    <sec sec-type="Introduction" id="sec2">
      <title>Introduction</title>
      <p>Postintubation tracheal stenosis provides a fundamental insight for clinical practice. During the patient’s preoperative preparation and throughout the surgical intervention, a multidisciplinary approach is employed. This approach incorporates a variety of surgical techniques concerning the following: trachea: addressing posttraumatic, postintubation, and iatrogenic complications; thyroid gland: addressing normal and pathological conditions; and proximal mediastinum and the nerve-vessel bundle of the neck.‌<sup>[<xref ref-type="bibr" rid="B1">1</xref>]</sup> Postintubation stenosis is induced by the intubation tube’s balloon mechanical pressure and ischemic tracheal damage, tracheal injury from a placed tracheostomy cannula with an inflated balloon, or a combination of both. It manifests clinically with stridor or unexplainable dyspnea after a period of mechanical ventilation. Most patients with this type of injury are candidates for tracheal resection and reconstruction.<sup>[<xref ref-type="bibr" rid="B2">2</xref>]</sup> The expected resection length is the most important determinative factor for the stenotic section’s resectability. The good surgical treatment principles require precise preoperative bronchoscopy assessment, full mobilization of the trachea intraoperatively, protection of both laryngeal recurrent nerves, precise anastomosis, and a motive regime by restricting the neck extension postoperatively.<sup>[<xref ref-type="bibr" rid="B3">3</xref>]</sup></p>
      <p>This case presents the clinical management of postintubation tracheal stenosis, emphasizing the surgical approach and the positive outcome achieved through a complex tracheal resection and anastomosis procedure.</p>
    </sec>
    <sec sec-type="Case report" id="sec3">
      <title>Case report</title>
      <p>S<italic>. A. was admitted to the Thoracic Surgery Department at Kaspela University Hospital in Plovdiv with respiratory complaints. The patient reported stridor and dyspnea after 10 days in hospital on mechanical ventilation due to aspiration pneumonia. The family of the patient reported his systematic alcohol abuse. There was no family history of exposure to harmful factors or previous surgical interventions</italic>.</p>
      <p><italic>The computed-axial tomography recorded unequally thickened tracheal walls distally to the cricoid cartilage ventral up to 0.8 cm with lumen stenosis up to 0.7 cm transversely by an extent of 2 cm</italic><bold><italic>(Figs <xref ref-type="fig" rid="F2">1</xref>, <xref ref-type="fig" rid="F1">2</xref>)</italic></bold>.</p>
      <fig id="F2">
        <object-id content-type="arpha">4617658D-2AD7-527E-8A78-AAB38F72D83E</object-id>
        <label>Figure 1.</label>
        <caption>
          <p>Preoperative <abbrev xlink:title="computed tomography">CT</abbrev> scan in axial view.</p>
        </caption>
        <graphic xlink:href="foliamedica-68-4-e156282-g002.jpg" id="oo_1761478.jpg">
          <uri content-type="original_file">https://binary.pensoft.net/fig/1761478</uri>
        </graphic>
      </fig>
      <fig id="F1">
        <object-id content-type="arpha">AB24F97A-8128-509B-B980-75DA7AE0F54B</object-id>
        <label>Figure 2.</label>
        <caption>
          <p>Preoperative <abbrev xlink:title="computed tomography">CT</abbrev> scan in sagittal view.</p>
        </caption>
        <graphic xlink:href="foliamedica-68-4-e156282-g001.jpg" id="oo_1761479.jpg">
          <uri content-type="original_file">https://binary.pensoft.net/fig/1761479</uri>
        </graphic>
      </fig>
      <p><italic>A hyperplastic multilayered flat epithelium was observed in the histopathological study of tissue taken via clip biopsy during video bronchoscopy from the stenotic area. Following all investigations and the multidisciplinary clinical council discussion, it was decided that the presented pathology should be treated surgically</italic>.</p>
      <p><italic>Under general anesthesia with an intubation tube No. 5 (as a larger size could not be passed through), after the operative field had been carefully cleaned, a Kocher’s cervicotomy incision was made. The trachea was reached layer by layer. The isthmus of the thyroid gland was cut between two ligatures. This was followed by a circular tracheal disengagement around 6 cm distal to the thyroid cartilage. Intraoperatively, video bronchoscopy was done by pulling out the intubation tube above the stenosis, and marking of the exact stenotic tracheal section location was performed</italic><bold><italic>(Fig. <xref ref-type="fig" rid="F3">3</xref>)</italic></bold>.   <italic>Circular resection of the stenotic section (2.5 cm). Reintubation via intubation tube No. 7. Positioning in the distal tracheal end. Termino-terminal anastomosis with one-layer catgut 3/0 prolene followed. Careful hemostasis. Hydraulic examination—no air-losing data. Flexible bronchoscopy surgery (<abbrev xlink:title="Flexible bronchoscopy surgery">FBS</abbrev>) repeatedly for anastomosis examination and repositioning of the intubation tube</italic><bold><italic>(Fig. <xref ref-type="fig" rid="F3">3</xref>)</italic></bold><italic>. Two contact drainages were placed. Suture the operative wound layer by layer. Two skin sutures of 2/0 Vicryl were placed on the mandible’s angle and parasternal on both sides to avoid neck extension</italic>.   <bold><italic>(Figs <xref ref-type="fig" rid="F5">4</xref>, <xref ref-type="fig" rid="F4">5</xref>)</italic></bold>  .</p>
      <fig id="F3">
        <object-id content-type="arpha">9B69BCFA-E6B4-5744-8DE8-30DCFE1F070C</object-id>
        <label>Figure 3.</label>
        <caption>
          <p>Intraoperative video bronchoscopy.</p>
        </caption>
        <graphic xlink:href="foliamedica-68-4-e156282-g003.jpg" id="oo_1761480.jpg">
          <uri content-type="original_file">https://binary.pensoft.net/fig/1761480</uri>
        </graphic>
      </fig>
      <fig id="F5">
        <object-id content-type="arpha">368456E8-D8EE-59D6-887B-D471CC2BC4E9</object-id>
        <label>Figure 4.</label>
        <caption>
          <p>Resected stenotic section of the trachea with a length of 2.5 cm.</p>
        </caption>
        <graphic xlink:href="foliamedica-68-4-e156282-g005.jpg" id="oo_1761481.jpg">
          <uri content-type="original_file">https://binary.pensoft.net/fig/1761481</uri>
        </graphic>
      </fig>
      <fig id="F4">
        <object-id content-type="arpha">77A2D522-58BA-535A-A9DC-F6101E3FCB7D</object-id>
        <label>Figure 5.</label>
        <caption>
          <p>Termino-terminal anastomosis of the trachea with 30 prolene.</p>
        </caption>
        <graphic xlink:href="foliamedica-68-4-e156282-g004.jpg" id="oo_1761482.jpg">
          <uri content-type="original_file">https://binary.pensoft.net/fig/1761482</uri>
        </graphic>
      </fig>
      <p><italic>Postoperatively, the patient was transferred to the anesthesiology and intensive care department on mechanical ventilation, hemodynamically stable without catecholamine support. Extubated on the first postoperative day. Calm operative wound, without active bleeding data from the drainages. The last ones were removed on the first postoperative day, and the patient was transferred to the thoracic surgery department. On the fourth postoperative day, control VBS for anastomosis assessment has been done. The same has been seen as intact without granulation or lumen narrowing data</italic><bold><italic>(Fig. <xref ref-type="fig" rid="F6">6</xref>)</italic></bold><italic>. On the seventh postoperative day, both sutures for limiting the head movements have been removed</italic>.</p>
      <fig id="F6">
        <object-id content-type="arpha">4DAC0B18-1F23-569C-98ED-A6057BB3A9A0</object-id>
        <label>Figure 6.</label>
        <caption>
          <p>Control video bronchoscopy on day 4 postoperatively.</p>
        </caption>
        <graphic xlink:href="foliamedica-68-4-e156282-g006.jpg" id="oo_1761483.jpg">
          <uri content-type="original_file">https://binary.pensoft.net/fig/1761483</uri>
        </graphic>
      </fig>
      <p><italic>Prior to being discharged from the hospital, a control computed-axial tomography of the thorax was performed. This imaging revealed that the anastomosis was intact and that the tracheal lumen was within normal parameters</italic><bold><italic>(Figs <xref ref-type="fig" rid="F7">7</xref>, <xref ref-type="fig" rid="F8">8</xref>)</italic></bold>  .</p>
      <fig id="F7">
        <object-id content-type="arpha">88996C5A-107E-58B5-9846-139A9B0EE7FB</object-id>
        <label>Figure 7.</label>
        <caption>
          <p>Postoperative <abbrev xlink:title="computed tomography">CT</abbrev> scan in axial view.</p>
        </caption>
        <graphic xlink:href="foliamedica-68-4-e156282-g007.jpg" id="oo_1761484.jpg">
          <uri content-type="original_file">https://binary.pensoft.net/fig/1761484</uri>
        </graphic>
      </fig>
      <fig id="F8">
        <object-id content-type="arpha">7E7EF283-FEC4-5525-9FB2-B19234F038FB</object-id>
        <label>Figure 8.</label>
        <caption>
          <p>Postoperative <abbrev xlink:title="computed tomography">CT</abbrev> scan in sagital view.</p>
        </caption>
        <graphic xlink:href="foliamedica-68-4-e156282-g008.jpg" id="oo_1761485.jpg">
          <uri content-type="original_file">https://binary.pensoft.net/fig/1761485</uri>
        </graphic>
      </fig>
      <p><italic>Histological investigation of the permanent hyperplastic multilayer flat epithelium. The patient was discharged in satisfying general condition</italic>.</p>
      <sec sec-type="Follow-up and resolution" id="sec4">
        <title>Follow-up and resolution</title>
        <p><italic>Following the initial management of postintubation tracheal stenosis, the patient was closely monitored through regular follow-up visits. At the first post-discharge consultation, clinical examination revealed no signs of respiratory distress or abnormal airway patency. A flexible bronchoscopy was performed to assess the tracheal lumen, which demonstrated satisfactory healing with no evidence of residual stenosis or complications. Pulmonary function tests, including spirometry, were conducted and indicated normal lung volumes and airflow, with no significant obstructions. The patient was instructed on maintaining a regimen of regular follow-up visits, with a repeat bronchoscopy scheduled for 6 months to ensure continued resolution. At the time of the latest review, the patient reported no respiratory symptoms, and their quality of life had returned to baseline levels. These findings suggest a favorable recovery trajectory, and the patient was discharged from active follow-up care with recommendations for annual monitoring</italic>.</p>
      </sec>
    </sec>
    <sec sec-type="Discussion" id="sec5">
      <title>Discussion</title>
      <p>Postintubation tracheal stenosis continues to present a serious surgical problem and a challenge for thoracic surgeons. The safety resection limit between 4 and 4.5 cm is narrow, and it requires exclusive precision and excellent mastery of multiple surgical techniques as well as many years of experience in tracheal surgery, as shown by Karapolat et al. In the study, several tracheal resections with end-to-end anastomosis had been performed, with the length of stenosis being from 2 to 4 cm.<sup>[<xref ref-type="bibr" rid="B4">4</xref>]</sup> The disengagement of the larynx usually leads to 1 cm–1.5 cm added length (it is required by around 4% of the patients), as seen in a study by Allen et al.<sup>[<xref ref-type="bibr" rid="B5">5</xref>]</sup> The performance of a control bronchoscopy on the 4th and 7th postoperative days is still the gold standard for anastomosis valuation.<sup>[<xref ref-type="bibr" rid="B6">6</xref>]</sup> It allows the investigation of unsuspected problems and their prompt eradication. With some patients developing granulations and/or necrosis on the anastomosis, an effective method (of choice) is the use of video-assisted bronchoscopy with photocoagulation or rigid bronchoscopy under general anesthesia, as demonstrated in a study published by Spittle et al.<sup>[<xref ref-type="bibr" rid="B7">7</xref>]</sup> The reintubation after such a surgery is usually a sign of poor surgical techniques and anastomosis performance, while sometimes it can be a necessity due to vocal cord or anastomosis edema that occurred, depending on the degree of obstruction, which can be graded by several proposed classifications, like the one suggested by Freitag et al.<sup>[<xref ref-type="bibr" rid="B8">8</xref>]</sup> Reintubation in general is related to a worse prognosis. The stenotic segment’s resection and the performance of a termino-terminal anastomosis remain the preferred operative method. The subglottic stenoses present a true challenge and predispose to allowing more mistakes—bad anastomosis technique and worse results. In case of an unsuccessful first resection, it is needed to wait 3-6 months before a repeated operation, and the purpose is to get the inflammatory process under control. Repeated <abbrev xlink:title="Flexible bronchoscopy surgery">FBS</abbrev> and dilation are preferred methods for providing stable airways.<sup>[<xref ref-type="bibr" rid="B9">9</xref>]</sup> The most common concomitant diseases that are presented by patients with postintubation tracheal stenosis are diabetes, obesity, and COPD (the decreased lung compliance requires higher ventilation pressure).<sup>[<xref ref-type="bibr" rid="B10">10</xref>]</sup> The increased frequency of tracheal stenosis in women is due to an estrogen-induced increase of the transformation growth factors and precipitation of collagen types 1 and 3, which leads to fibrosis.<sup>[<xref ref-type="bibr" rid="B11">11</xref>]</sup> Tracheal stenoses increased in frequency after intubation during the COVID-19 pandemic due to the long-term ventilation. It gets worse from the theory that the repeated cycles of ventilation on someone’s abdomen (prone position) can increase the intraluminal tube’s pressure in the anterior or posterior part of the glottis, increasing the stenosis formation risk.<sup>[<xref ref-type="bibr" rid="B12">12</xref>,<xref ref-type="bibr" rid="B13">13</xref>]</sup> Many of these patients with COVID-19 with postintubation tracheal stenosis are shown with late symptoms after discharge from the ICU, and that is the reason a purposeful evaluation for excluding postintubation tracheal stenosis is recommended. In the case of the right patient’s selection, good perioperative preparation, and thorough discussion from multidisciplinary teams, the success rate is over 90%.<sup>[<xref ref-type="bibr" rid="B14">14</xref>]</sup> The most common complication after tracheal resection and anastomosis is suture line granulations, which have almost vanished with the use of absorbable sutures, as reported in a study by Grillo including 503 patients.<sup>[<xref ref-type="bibr" rid="B11">11</xref>,<xref ref-type="bibr" rid="B15">15</xref>]</sup></p>
    </sec>
    <sec sec-type="Conclusion" id="sec6">
      <title>Conclusion</title>
      <p>Effective management of postintubation tracheal stenosis hinges on early diagnosis, precise imaging, and a multidisciplinary surgical approach. This case demonstrates that meticulous planning and expertise in tracheal surgery can achieve excellent outcomes, restoring airway function and quality of life. Ongoing postoperative monitoring ensures sustained recovery, reinforcing the value of a systematic, patient-centered strategy. Achieving reliable outcomes in the treatment of postintubation tracheal stenosis requires meticulous patient selection, comprehensive preoperative evaluation, and careful preparation. As demonstrated in the clinical case reported, adherence to fundamental principles of tracheal surgery—first outlined over five decades ago—remains critical. In addition to this foundational knowledge, the surgeon’s proficiency in a broad range of specialized techniques directly influences surgical success and patient recovery. Timely and accurate diagnosis, effective multidisciplinary collaboration, and consistent postoperative monitoring were also key elements contributing to the favorable outcome in our case. These findings are well-supported by current medical literature, which consistently emphasizes the importance of a systematic and collaborative approach in managing this complex condition.</p>
    </sec>
  </body>
  <back>
    <ref-list>
      <title>References</title>
      <ref id="B1">
        <label>1.</label>
        <mixed-citation>Hashemzadeh S, Hashemzadeh K, Kakaei F, et al. Surgical treatment of postintubation tracheal stenosis: Iranian experience of effect of previous tracheostomy. Int J Gen Med 2012; 5:93–8. <ext-link ext-link-type="doi" xlink:href="10.2147/IJGM.S27559">doi: 10.2147/IJGM.S27559</ext-link></mixed-citation>
      </ref>
      <ref id="B2">
        <label>2.</label>
        <mixed-citation>De Sajal, De S. Post intubation tracheal stenosis. Indian J Crit Care Med 2008;12(4):194-7. <ext-link ext-link-type="doi" xlink:href="10.4103/0972-5229.45081">doi: 10.4103/0972-5229.45081</ext-link></mixed-citation>
      </ref>
      <ref id="B3">
        <label>3.</label>
        <mixed-citation>Mathisen DJ. Tracheal resection and reconstruction: how I teach it. Ann Thorac Surg 2017; 103(4):1043–8. <ext-link ext-link-type="doi" xlink:href="10.1016/j.athoracsur.2016.12.057">doi: 10.1016/j.athoracsur.2016.12.057</ext-link></mixed-citation>
      </ref>
      <ref id="B4">
        <label>4.</label>
        <mixed-citation>Karapolat S, Turkyilmaz A, Seyis KN, et al. A comfortable solution to tracheal anastomosis protection: tracheal retention sutures. Heart Lung Circ 2018; 27(4):e39–e41. <ext-link ext-link-type="doi" xlink:href="10.1016/j.hlc.2017.09.012">doi: 10.1016/j.hlc.2017.09.012</ext-link></mixed-citation>
      </ref>
      <ref id="B5">
        <label>5.</label>
        <mixed-citation>Allen MS. Surgery of the trachea. Korean J Thorac Cardiovasc Surg 2015; 48(4):231–7. <ext-link ext-link-type="doi" xlink:href="10.5090/kjtcs.2015.48.4.231">doi: 10.5090/kjtcs.2015.48.4.231</ext-link></mixed-citation>
      </ref>
      <ref id="B6">
        <label>6.</label>
        <mixed-citation>Stauffer JL, Olson DE, Petty TL. Complications and consequences of endotracheal intubation and tracheotomy. A prospective study of 150 critically ill adult patients. Am J Med 1981; 70(1):65–76. <ext-link ext-link-type="doi" xlink:href="10.1016/0002-9343(81)90413-7">doi: 10.1016/0002-9343(81)90413-7</ext-link></mixed-citation>
      </ref>
      <ref id="B7">
        <label>7.</label>
        <mixed-citation>Spittle N, McCluskey A. Lesson of the week: tracheal stenosis after intubation. BMJ 2000; 321(7267):1000–2. <ext-link ext-link-type="doi" xlink:href="10.1136/bmj.321.7267.1000">doi: 10.1136/bmj.321.7267.1000</ext-link></mixed-citation>
      </ref>
      <ref id="B8">
        <label>8.</label>
        <mixed-citation>Freitag L, Ernst A, Unger M, et al. A proposed classification system of central airway stenosis. Eur Respir J 2007; 30(1):7–12. <ext-link ext-link-type="doi" xlink:href="10.1183/09031936.00132804">doi: 10.1183/09031936.00132804</ext-link></mixed-citation>
      </ref>
      <ref id="B9">
        <label>9.</label>
        <mixed-citation>Wain JC Jr. Postintubation tracheal stenosis. Semin Thorac Cardiovasc Surg 2009; 21(3):284–9. <ext-link ext-link-type="doi" xlink:href="10.1053/j.semtcvs.2009.08.001">doi: 10.1053/j.semtcvs.2009.08.001</ext-link></mixed-citation>
      </ref>
      <ref id="B10">
        <label>10.</label>
        <mixed-citation>Uğur Chousein EG, Özgül MA. [Postintubation tracheal stenosis]. Tuberk Toraks 2018; 66(3):239–48. <ext-link ext-link-type="doi" xlink:href="10.5578/tt.67108">doi: 10.5578/tt.67108</ext-link> [Turkish].</mixed-citation>
      </ref>
      <ref id="B11">
        <label>11.</label>
        <mixed-citation>Grillo HC, Donahue DM, Mathisen DJ, et al. Postintubation tracheal stenosis. Treatment and results. J Thorac Cardiovasc Surg 1995; 109(3):486–92; discussion 492-3. <ext-link ext-link-type="doi" xlink:href="10.1016/S0022-5223(95)70279-2">doi: 10.1016/S0022-5223(95)70279-2</ext-link></mixed-citation>
      </ref>
      <ref id="B12">
        <label>12.</label>
        <mixed-citation>Karnan A, Wagh P. Post-intubation tracheal stenosis: a rare clinical image. Pan Afr Med J 2024; 47:135. <ext-link ext-link-type="doi" xlink:href="10.11604/pamj.2024.47.135.42756">doi: 10.11604/pamj.2024.47.135.42756</ext-link></mixed-citation>
      </ref>
      <ref id="B13">
        <label>13.</label>
        <mixed-citation>Brichet A, Verkindre C, Dupont J, et al. Multidisciplinary approach to management of postintubation tracheal stenoses. Eur Respir J 1999; 13(4):888–93. <ext-link ext-link-type="doi" xlink:href="10.1034/j.1399-3003.1999.13d32.x">doi: 10.1034/j.1399-3003.1999.13d32.x</ext-link></mixed-citation>
      </ref>
      <ref id="B14">
        <label>14.</label>
        <mixed-citation>Wright CD, Li S, Geller AD, et al. Postintubation tracheal stenosis: management and results 1993 to 2017. Ann Thorac Surg 2019; 108(5):1471–7. <ext-link ext-link-type="doi" xlink:href="10.1016/j.athoracsur.2019.05.050">doi: 10.1016/j.athoracsur.2019.05.050</ext-link></mixed-citation>
      </ref>
      <ref id="B15">
        <label>15.</label>
        <mixed-citation>Sısman M, Topaloglu O, Karapolat S, et al. Surgical outcomes following tracheal reconstruction in patients with post-intubation tracheal stenosis. Turk Gogus Kalp Damar Cerrahisi Derg 2025; 33(1):68–76. <ext-link ext-link-type="doi" xlink:href="10.5606/tgkdc.dergisi.2025.26979">doi: 10.5606/tgkdc.dergisi.2025.26979</ext-link></mixed-citation>
      </ref>
    </ref-list>
    <sec sec-type="Additional information" id="sec7">
      <title>Additional information</title>
      <p>
        <bold>Ethical statement</bold>
      </p>
      <list list-type="bullet">
        <list-item>
          <p>The authors declared that no clinical trials were used in the present study.
</p>
        </list-item>
        <list-item>
          <p>The authors declared that no experiments on humans or human tissues were performed for the present study.
</p>
        </list-item>
        <list-item>
          <p>The authors declared that no informed consent was obtained from the humans, donors or donors’ representatives participating in the study.
</p>
        </list-item>
        <list-item>
          <p>The authors declared that no experiments on animals were performed for the present study.
</p>
        </list-item>
        <list-item>
          <p>The authors declared that no commercially available immortalized human and animal cell lines were used in the present study.
</p>
        </list-item>
      </list>
      <p>
        <bold>Conflict of interest</bold>
      </p>
      <p>The authors have declared that no competing interests exist.</p>
      <p>
        <bold>Artificial Intelligence (AI) use</bold>
      </p>
      <p>The authors accept full responsibility for the content of the manuscript, including the disclosure of any use of AI. No AI tools were used in the preparation of this manuscript.</p>
      <p>
        <bold>Funding</bold>
      </p>
      <p>No funding was reported.</p>
      <p>
        <bold>Author contributions</bold>
      </p>
      <p>All authors have contributed equally.</p>
      <p>
        <bold>Author ORCIDs</bold>
      </p>
      <p>Boyko Yavorov <ext-link xlink:href="https://orcid.org/0009-0003-3980-3599" ext-link-type="uri">https://orcid.org/0009-0003-3980-3599</ext-link></p>
      <p>Vladimir Aleksiev <ext-link xlink:href="https://orcid.org/0009-0004-7860-6632" ext-link-type="uri">https://orcid.org/0009-0004-7860-6632</ext-link></p>
      <p>
        <bold>Data availability</bold>
      </p>
      <p>All of the data that support the findings of this study are available in the main text.</p>
    </sec>
  </back>
</article>
