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Article title
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Abstract
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Keywords
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Introduction
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Materials and methods
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Animal model
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Experimental design
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Sample size estimation
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Appliance fabrication and functional advancement protocol
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Sample collection
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Gene expression analysis
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Histological analysis
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Statistical analysis
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Results
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Gene expression in masticatory muscles
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Myostatin gene expression in masticatory muscles
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Comparison of myostatin expression in masseter and lateral pterygoid muscles
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MYO1C gene expression in masticatory muscles
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Comparison of MYO1C expression in the masseter and lateral pterygoid muscles
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Histological analysis
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Masseter muscle
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Lateral pterygoid muscle
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Comparison between masseter and lateral pterygoid muscles
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Discussion
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Clinical relevance: beyond orthodontics – broader impact of our mandibular advancement study
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Limitations and future directions
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Conclusion
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Ethical approval
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Ethical statements
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Conflict of interest
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Use of AI
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Funding
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Author contributions
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Data availability
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Acknowledgements
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References
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