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  • Article title
  • Keywords
  • Introduction
  • Developmental differences in the physiological response to exercise
  • Key parameters of interest in pediatric CPET
    • Oxygen consumption (VO2)
    • Ventilatory thresholds
    • Respiratory exchange ratio (RER)
    • Ventilatory efficiency and its slope (VE/VCO2 slope)
    • Oxygen uptake efficiency and oxygen uptake efficiency slope
  • Criteria for maximal effort in children
  • Methodological specificities of CPET in children
    • Pediatric CPET equipment
    • Protocol selection
    • Motivational and compliance issues
  • Safety considerations and contraindications to CPET in children
  • Clinical applications of CPET in children
    • Fitness evaluation in children
    • CPET in obese children
    • CPET in children with chronic respiratory diseases
    • CPET in children with congenital heart defects and heart failure
  • Challenges and future directions in pediatric CPET
  • Conclusion
  • Acknowledgements
  • References
  • Additional information
    • Ethical statements
    • Conflict of interest
    • Artificial Intelligence (AI) Use
    • Funding
    • Author ORCIDs
    • Data availability
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