Distribution of immunoreactivity for CRP – it has an increased expression in the undifferentiated spermatogonia, round and elongated spermatids, head and tail of mature sperm and Leydig cells from group E compared to group C – visualised mainly in the steroid-producing cells in the interstitium; IL-4 had higher expression in the Leydig cells from the interstitium, the undifferentiated spermatogonia, spermatocytes, elongated spermatids, and the tail of mature sperm from group C compared to group E; SAA was predominantly expressed in the Leydig cells and undifferentiated spermatids from group E compared to the control group where it was not visualized. We found increased ACE expression in the round, elongated, and mature sperm from both groups. The ACE expression from group E was also found in the steroid-producing cells from the interstitium of the testes. Е: experimental group; С: control group. (magnification ×400).