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  • Article title
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  • Introduction
    • Radiation therapy-related toxicity, an interplay of genetics and other determinants
    • Dosimetry and clinical severity
    • Chronic RT damage, really a persisting medical need
    • The rationale for polynucleotides in the prevention and treatment of RT-induced skin and mucosal disorders
    • Clinical experience with polynucleotides in the prevention of RT-induced acute and chronic skin and mucosal disorders
    • The extensive RT experience with topical polynucleotides over the more recent years
  • Conclusions
  • Acknowledgements
  • Competing interests
  • Data resources
  • Author contributions
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