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  • Article title
  • Keywords
  • Introduction
  • Aim
  • Materials and methods
    • Materials
    • Methods
      • Preparation of canagliflozin nanosuspension
      • Characterisation of canagliflozin nanosuspension
      • Preparation of immediate release pellets
      • Formulation and optimisation of canagliflozin pellets by using 2 3 factorial design
      • Characterisation of drug loaded pellets
  • Results and discussion
    • Characterisation and optimisation of canagliflozin nanosuspension
    • Evaluation of immediate release pellets
    • Density and flow properties
    • Friability
    • Drug content
    • Particle size
    • Disintegration time
    • Data analysis
    • X-ray diffraction
    • Fourier transform spectroscopy analysis
    • Differential scanning calorimetry (DSC)
    • Scanning electron microscopy
  • Conclusions
  • Acknowledgements
  • References
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