"Anti TB Drug";"Genomic region";Gene;"Detected mutation by WGS, n";pDST
Rifampicin;Rv0667;rpoB;"Ser450Leu (tcg/tTg), n=47 His445Asp (cac/Gac), n=5 Asp435Val (gac/gTc), n=2 Ser450Trp (tcg/tGg), n=2 Leu430Pro (ctg/cCg), n=1 Ser441Leu (tcg/tTg), n=1 Gln432Pro (caa/cCa), n=1 Val170Phe (gtc/Ttc), n=1";"R n= 47 R n=5 R n=2 R n=2 R n=1 R n=1 R n=1 R n=1"
Isoniazid;Rv1483;"inhA promoter region";"C-15T (atc/aCc), n=26";"R n= 26"
Rv1908c;katG;"Ser315Thr (agc/aCc), n=18 Ser315Asn (agc/aAc), n=1";"R n= 18 R n=1"
;;"Co-occurrence  inhA+katG mutation, n=3";"R n=3"
Rv2428;ahpC;"C-57T, n=1";"R n=1"
;;"Not found";"R n=2; S n=9"
Ethambutol;Rv3795;embB;"Met306Val (atg/Gtg), n=25 Met306Ile (atg/atA), n=8 Ala454Thr (gcg/Acg), n=2 Gly406Asp (ggc/gAc), n=2 Ser297Ala (tcg/Gcg), n=2 Gln497Lys (cag/Aag), n=1 snp 4243225 C A, n=1";"R n=24; S n=1 R n=3; S n=5 S n=2 S n=2 R n=1; S n=1 S n=1 S n=1"
Pyrazinamide;Rv2043c;pncA;"Pro69Leu (cca/cTa), n=3 His82Arg (cat/cGt), n=6 Leu4Ser (ttg/tCg), n=2 His137Pro (cat/cCt), n=1 Thr76Pro (act/Cct), n=1 Gly105Asp (ggc/gAc), n=1 ins 2288846 A C, n=4 ins 2288708 G C, n=1";"Not performed"
Fluoroquinolones;Rv0006;gyrA;"Ala90Val (gcg/gTg), n=8 Asp94Gly (gac/gGc), n=2 Gly88Ala (ggc/gCc), n=1";"R n=1; S n=7 R n=2 S n=1"
Rv0005;gyrB;"Not found";
;;"co-occurrence gyrA Ala90Val (gcg/gTg)+gyrB Ala 504 Val (gcg/gTg), n=1";"R n=1"
"Amikacin, kanamycin, capreomycin";Rvnr01;rrs;"A1401G, n=3";"R n=3"
Kanamycin;Rv2416c;eis;"Not found";
Capreomycin;Rv1694;tlyA;"Not found";
Streptomycin;"Rv0682  Rvnr01";"rpsL  rrs";"Lys43Arg (aag/aGg), n= 2 Lys88Arg (aag/aGg), n= 2 C517T, n=5 A514C, n=8";"R n=2 R n=2 R n=5 R n=8"
Bedaquiline;Rv0678;mmpR;"Not found";"Not performed"
Rv1305;atpE;"Not found"