The children were characterized as having a pleasant and affectionate demeanor. Most were short in stature and presented with distinctive features of the craniofacial area. Such features included microcephaly with a high forehead, an elongated face, widely spaced eyes, down-slanted palpebral fissure, thin upper lip, a flat nasal bridge with a prominent nasal tip, large low-set ears, micrognathia, and a high palate.