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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Aim
  • Materials and methods
    • Chemicals and reagents
    • Composition and preparation of nitrofurantoin model vehicles
    • UV-Vis spectrophotometric determination of nitrofurantoin
    • Sedimentation volume monitoring
    • pH determination of nitrofurantoin suspension models
    • Rheological analysis
    • Determination of variation in nitrofurantoin concentrations in the model suspensions through reverse-phase high-efficiency liquid chromatography (RP-HPLC/UV)
      • Instruments
      • Chromatographic conditions
      • Sample preparation
      • Validation of the HPLC method
      • Microbiological stability
    • Statistical analysis
  • Results
    • Preliminary UV-Vis spectrophotometrical determination of content uniformity of nitrofurantoin
    • Sedimentation volume monitoring
    • Rheological analysis
    • Determination of variation in nitrofurantoin concentrations in the model suspensions through reverse-phase high-performance liquid chromatography (RP-HPLC/UV)
    • Microbiological stability
  • Discussion
  • Conclusions
  • Acknowledgements
  • Funding
  • Competing Interests
  • References
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