;"dn-AML-MDS n=30)";"AML-post-MDS (n=30)";"AML-post-MPN (n=20)";"CML-BC (n=14)";"p value"
"Demographic parameters"
Male:female;1.14:1;1.64:1;1.44:1;1.6:1;NS
"Age, (years) (mean±SD)";64.4±11.9;62±16.6;63.4±11.5;46.9±13.8;0.005
"Hematological indexes"
"Hgb, (g/L) (mean±SD)";81.3±18.2;82.2±15.6;84.4±20.5;78.9±20.3;NS
"WBC, (×109/L) (mean±SD)";15.5±33.8;26.3±43.3;73.1±81.4;133.2±154.5;<0.001
"PLT, (×109/L) (mean±SD)";92.5±107.8;75.3±102.3;156.4±188.4;278.1±241.8;0.001
"Bone marrow morphology"
"% blasts (mean±SD)";42.4±17.4;45.8±21.5;55.1±25.6;29.8±17.4;NS
"Dysgranulocytopoiesis, (%)";96.55%;61.54%;44.44%;20.00%;<0.001
"Dyserythropoiesis, (%)";48.28%;57.69%;22.20%;0.00%;NS
"Dysmegakaryocytopoiesis, (%)";72.41%;61.54%;55.55%;20.00%;NS
"Dysplasia in >2 cell lineages, (%)";96.55%;100.00%;33.33%;0%;<0.001
Phenotype
"CD13, (% pos. pts)";93.33%;88.46%;75.00%;81.82%;NS
"CD33, (% pos. pts)";93.33%;88.46%;93.75%;100.00%;NS
"CD64, (% pos. pts)";50.00%;34.62%;25.00%;9.09%;NS
"CD117, (% pos. pts)";100.00%;88.46%;93.75%;100.00%;NS
"MPO, (% pos. pts)";53.33%;42.31%;25.00%;36.36%;NS
"Lymphoid-associated markers, (% pos. pts)";70.00%;65.39%;50.00%;90.91%;NS
">2 lymphoid-associated markers, (% pos. pts)";36.67%;26.93%;37.50%;45.46%;NS
"Cytogenetic and molecular aberrations"
"Normal karyotype, (% pts)";"25% (6/24)";"58.3% (14/24)";"33.3% (2/6)";"42.2% (5/11)";NS
"Aberrant karyotype, (% pts)";75%;41.7%;66.7%;57.8%;NS
"Complex karyotype, (% pts)";"45.8% (11/24)";"20.8% (5/24)";"50% (3/6)";0%;0.05
"Unbalanced abnormalities";"16.7% (4/24)";20.8%;"16.7% (1/6)";"40.0% (4/10)";0.05
"Balanced abnormalities";"12.5% (3/24)";0%;0%;"10.0% (1/10)";0.05
"Chromosome 5, (% pts)";40.0%;29.2%;33.3%;0.00%;0.053
"Chromosome 7, (% pts)";36.0%;8.3%;0.00%;0.00%;0.012
"FLT3-ITD, (% pts)";4.5%;26.3%;25.0%;NA;0.049*
"EVI1 overexpression, (% pts)";5.0%;13.3%;37.5%;80.0%;0.001
"NPM1 mutation, (% pts)";9.5%;20.0%;50.0%;NA;NS
"Clinical course"
"TTL months, (median±SD)";NA;4.80±1.0;20.3±2.9;34.7±16.3;0.008
"OS months (median±SD)";6.17±2.77;4.17±0.77;5.17±2.79;13.67±4.58;NS