Histological evaluation of rat hearts regarding presence or absence of endocarditic changes of the aortic valve in percent. The endocarditis group (EG, n=13) received dental ligation and catheter-induced injury of the aortic valve, the antibiosis group (AG, n=12) also received dental ligation and catheter-induced injury of the aortic valve with additional single-shot antibiosis, and the control group (PG, n=10) received dental ligation only. ** p<0.05 in chi-square test for trend between ‘endocarditis’ and ‘antibiosis’ and ‘endocarditis’ and ‘antibiosis’.