Nikolaos Blontzos‡, Christos Iavazzo‡, Eirini Giovannopoulou‡, George Galanopoulos‡, Victoria Psomiadou‡, George Vorgias‡Corresponding author: Nikolaos Blontzos ( nikolas.mplontzos@yahoo.gr ) © Nikolaos Blontzos, Christos Iavazzo, Eirini Giovannopoulou, George Galanopoulos, Victoria Psomiadou, George Vorgias. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation:
Blontzos N, Iavazzo C, Giovannopoulou E, Galanopoulos G, Psomiadou V, Vorgias G (2020) Primary Peritoneal Serous Carcinoma Detected by Abnormal Cervical Smear: a Case Report. Folia Medica 62(1): 195-199. https://doi.org/10.3897/folmed.62.e47875 |  |
Primary peritoneal serous carcinoma (PPSC) is a rare malignancy, the clinical characteristics of which resemble ovarian serous carcinoma. We present a rare case of PPSC detected by an abnormal cervical smear, the first one with an absence of ovarian tissue at the time of the initial diagnosis.
A 59-year-old asymptomatic woman presented with glandular atypia on routine Papanicolaou smear. Endocervical and endometrial curettage showed an adenocarcinoma with focal squamous differentiation and uncertain further classification. The patient had a past surgical history of bilateral salpingoophorectomy due to endometriosis. Abdominal MRI depicted omental multinodularity, great amount of ascites and possible endometrial tumor. The patient underwent total hysterectomy, omentectomy and biopsies of implants on Douglass pouch. Surgical and histological findings were consistent with primary peritoneal serous carcinoma.
Abnormal pap smear could rarely be suggestive of extrauterine malignancies, such as peritoneal cancer.