Folia Medica 61(4): 650-654, doi: 10.3897/folmed.61.e47962
Therapy with L-thyroxine and Omnadren after Cardiac Surgery. A Case Report
expand article infoGeorgi J. Stoitsev§, Veselin Gavrilov|, Georgi Manchev§, Boyan Markov§, Valya Goranovska§, Boris Tsankov, Vassil Gegouskov§
‡ Medical University - Pleven, Pleven, Bulgaria§ St Anna University Hospital, Sofia, Bulgaria| Medical University - Sofia, Sofia, Bulgaria
Open Access
Abstract

Background: Cardiopulmonary bypass in cardiac surgery produces systemic inflammatory response and catabolic state. Severe stress frequently causes abnormalities in thyroid hormones in the absence of primary thyroid disease, defined as sick euthyroid syndrome (SES).

Materials and methods: Supplementation therapy with thyroid and anabolic hormones in combination with an adequate nutritional support has been used to improve outcome in critically ill patient after cardiac surgery.

Results: Administration of thyroid and anabolic hormones significantly improved patient’s condition.

Conclusions: Supplementation therapy with thyroid and anabolic hormones in combination with an adequate nutritional support could be used to improve hemodynamics, achieve transition to anabolic metabolism and enhance recovery, which could eventually help for a reduction in post-operative morbidity and mortality.

Keywords
anabolic metabolism, cardiac surgery, L-thyroxine, nutrition, testosterone