Folia Medica 62(1): 190-194, doi: 10.3897/folmed.62.e49813
Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma
expand article infoSpasimir Shopov§
‡ MBAL "Parvomai'' Ltd, Parvomai, Bulgaria§ Medical University, Plovdiv, Bulgaria
Open Access
In endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endometrium is currently not included in the latest classification of the tumors in the female reproductive system, its existence provokes an interest due to the necessity to perform differential diagnosis against other endometrioid tumors. Hereby presented is a case of papillary endometrioid carcinoma of intermediate grade with invasion in leiomyoma, expressed via LVSI and MELF syndrome with intact myometrium. Morphological and immunohistochemical algorithms have been performed.
carcinoma, immunohistochemical, leiomyoma, uterus