Vasko Graklanov‡, Veselin Popov‡, Ralitsa Raycheva‡Corresponding author: Vasko Graklanov ( dr.grklanov@yahoo.com ) © Vasko Graklanov, Veselin Popov, Ralitsa Raycheva. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation:
Graklanov V, Popov V, Raycheva R (2020) Serum Levels of Vitamin D in Patients with Multiple Myeloma. Folia Medica 62(4): 730-735. https://doi.org/10.3897/folmed.62.e50321 |  |
Aim: То investigate the serum levels of vitamin D in newly diagnosed patients with multiple myeloma.
Patients and methods: In this study we measured the serum levels of vitamin D in 37 patients (19 women, 18 men) at a median age of 68 years and a diagnosis of MM according to the International Myeloma Working Group (IMWG) criteria. The immunoassay tests used for the quantification of 25 (OH) – Vitamin D were original ELISA kits Immundiagnostic and the measurement was done before starting the treatment.
Results: Serum levels below the optimum (<30 ng/ml) were recorded in all 37 patients. The median value of vitamin D was 4.3±6.5 mg/ml, the maximum value measured was 24.7 mg/ml, which is below the lower limit of the reference value for deficiency.
Conclusions: In this study, we found extremely low serum vitamin D levels in most of the newly diagnosed MM patients.