Folia Medica 62(4): 730-735, doi: 10.3897/folmed.62.e50321
Serum Levels of Vitamin D in Patients with Multiple Myeloma
expand article infoVasko Graklanov, Veselin Popov, Ralitsa Raycheva
‡ Medical University of Plovdiv, Plovdiv, Bulgaria
Open Access

Aim: То investigate the serum levels of vitamin D in newly diagnosed patients with multiple myeloma.

Patients and methods: In this study we measured the serum levels of vitamin D in 37 patients (19 women, 18 men) at a median age of 68 years and a diagnosis of MM according to the International Myeloma Working Group (IMWG) criteria. The immunoassay tests used for the quantification of 25 (OH) – Vitamin D were original ELISA kits Immundiagnostic and the measurement was done before starting the treatment.

Results: Serum levels below the optimum (<30 ng/ml) were recorded in all 37 patients. The median value of vitamin D was 4.3±6.5 mg/ml, the maximum value measured was 24.7 mg/ml, which is below the lower limit of the reference value for deficiency.

Conclusions: In this study, we found extremely low serum vitamin D levels in most of the newly diagnosed MM patients.

chemotherapy, multiple myeloma, radiotherapy, vitamin D