Folia Medica 62(4): 861-865, doi: 10.3897/folmed.62.e50349
Treatment of Corticosteroid Non-responsive Relapse of Neuromyelitis Optica with Intravenous Gamma Globulin – a Case Report
expand article infoMaria Dimitrova‡, Dobromir Iliev‡
‡ NI Pirogov University Hospital for Emergency Care, Sofia, Bulgaria

Corresponding author: Maria Dimitrova ( dr.m.i.dimitrova@gmail.com )

© Maria Dimitrova, Dobromir Iliev.
This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Citation: Dimitrova M, Iliev D (2020) Treatment of Corticosteroid Non-responsive Relapse of Neuromyelitis Optica with Intravenous Gamma Globulin - a Case Report. Folia Medica 62(4): 861-865. https://doi.org/10.3897/folmed.62.e50349
Open Access
Abstract

We report a case of a patient with a relapse of neuromyelitis optica. The relapse was initially treated with intravenous corticosteroids. A therapy with intravenous gamma globulin was started as there was no symptomatic improvement. The patient responded well to the treatment with no significant side effects. Worldwide experience with gamma globulin treatment of neuromyelitis optica is limited and randomised control trials are lacking, therefore accumulation of data from case reports is of paramount importance.

Keywords
corticosteroid, intravenous gamma globulin, neuromyelitis optica, relapse