Folia Medica 63(2): 297-301, doi: 10.3897/folmed.63.e54665
Unexpected hearing improvement after treatment with valganciclovir in a child with congenital cytomegalovirus infection
Silvia Palma‡, Laura Mazzoni§, Maria Federica Roversi§, Cecilia Botti§, Daniele Monzani§, Alberto Berardi§, Elisabetta Genovese§‡ Primary Care Unit, Modena, Italy§ University of Modena and Reggio Emilia, Modena, Italy
Corresponding author: Cecilia Botti ( botceci@gmail.com ) © Silvia Palma, Laura Mazzoni, Maria Federica Roversi, Cecilia Botti, Daniele Monzani, Alberto Berardi, Elisabetta Genovese. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation:
Palma S, Mazzoni L, Roversi MF, Botti C, Monzani D, Berardi A, Genovese E (2021) Unexpected hearing improvement after treatment with valganciclovir in a child with congenital cytomegalovirus infection. Folia Medica 63(2): 297-301. https://doi.org/10.3897/folmed.63.e54665 |  |
Abstract
A 32-week preterm-born male with symptomatic congenital cytomegalovirus infection was treated with valganciclovir. He was also affected by congenital severe bilateral hearing loss and, unexpectedly, a normalization of the hearing threshold was reached at one year of age. The improvement of hearing level in relationship with both the late development of the auditory system and the administration of antiviral therapy is discussed. This case also highlights the importance of early diagnosis of congenital cytomegalovirus associated with close follow-up.
Keywords
CMV, congenital, cytomegalovirus, hearing, hearing loss, valganciclovir