Folia Medica 63(3): 309-314, doi: 10.3897/folmed.63.e54750
Sporadic spinal schwannomas and neurofibromas - a review
expand article infoGeorgi Apostolov, Borislav Kitov§, Elena Poryazova|, Ivo Kehayov§
‡ Clinic of Neurosurgery, Sv Georgi University Hospital, Plovdiv, Bulgaria§ Department of Neurosurgery, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria| Department of General and Clinical Pathology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
Open Access
Abstract
Tumours arising from the spinal nerve roots are more common in men between the third and fourth decades of life, located mainly in the intradural space of the lumbar region. The clinical symptoms of spinal schwannomas and neurofibromas are similar and depend on the location of the tumour and its relationship to the spinal cord and nerve roots. The pain (radiculalgia and/or vertebralgia) is the earliest symptom, followed by sensory deficit, while motor deficits and sphincter disorders are late symptoms. Magnetic resonance imaging is the diagnostic tool of choice and should be performed when the disease is suspected, as early and accurate diagnosis is essential for treatment outcome. The treatment of these lesions is surgical aiming at total tumour resection that promotes neurological recovery and prevents from recurrences. Subtotal removal also provides favourable outcome but at higher recurrence rates. The aim of this literature review was to study some important characteristics of sporadic spinal schwannomas (SSS) and neurofibromas (SSN), i.e. those not
associated with neurofibromatosis type I and II.
Keywords
MRI, neurofibroma, outcome, schwannoma, surgery