Folia Medica 63(6): 985-989, doi: 10.3897/folmed.63.e57633
Primary Bartholin Adenocarcinoma: a Rare Case and Radiotherapy as Definitive Treatment
expand article infoLokot Donna Lubis, Sarah Dina§, Derissa Khairina Khaidirman|
‡ Histology Department, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia§ Obstetric and Gynaecologic Department, Haji Adam Malik Hospital, Medan, Indonesia| Royal Prima Hospital, Medan, Indonesia
Open Access

Primary vulvar adenocarcinoma is a very rare neoplasm, accounting for only 1% of all gynecologic malignancies. Most of the glandular carcinomas originated from the Bartholin’s gland. Because of the rare incidence, the pathogenesis and radiotherapy response are not fully understood. A 47-year-old female from our hospital was diagnosed with primary Bartholin adenocarcinoma and received radiotherapy as definitive treatment. We evaluated the presence of high-risk and low-risk human papillomavirus (HPV) DNA to associate the role of HPV infection, and evaluated its molecular features by the expression of vimentin, p16, estrogen receptor, progesterone receptor, S-100, and Ki 67.

Bartholin’s gland adenocarcinoma, radiotherapy, vulvar cancer