Lokot Donna Lubis‡, Sarah Dina§, Derissa Khairina Khaidirman|Corresponding author: Lokot Donna Lubis ( 2lokdonlub@gmail.com ) © Lokot Donna Lubis, Sarah Dina, Derissa Khairina Khaidirman. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation:
Lubis LD, Dina S, Khaidirman DK (2021) Primary Bartholin Adenocarcinoma: a Rare Case and Radiotherapy as Definitive Treatment. Folia Medica 63(6): 985-989. https://doi.org/10.3897/folmed.63.e57633 |  |
Primary vulvar adenocarcinoma is a very rare neoplasm, accounting for only 1% of all gynecologic malignancies. Most of the glandular carcinomas originated from the Bartholin’s gland. Because of the rare incidence, the pathogenesis and radiotherapy response are not fully understood. A 47-year-old female from our hospital was diagnosed with primary Bartholin adenocarcinoma and received radiotherapy as definitive treatment. We evaluated the presence of high-risk and low-risk human papillomavirus (HPV) DNA to associate the role of HPV infection, and evaluated its molecular features by the expression of vimentin, p16, estrogen receptor, progesterone receptor, S-100, and Ki 67.